Scientists have solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells. A team of scientists headed by Rosalind Franklin ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of ...

The primary functions of the proteasome are driven by a highly allosteric ATPase complex. ATP binding to only two subunits in this hexameric complex triggers substrate binding, ATPase–20S ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans, has ...

Thus, mitochondrial Hsp70 fulfills a dual function in the formation of ATP synthase: the assembly of the catalytic head and the controlled linkage of the head to the stator.

Researchers have successfully reconstructed and solved the structure of mitochondrial ATP synthase with native lipids.

SciLifeLab researchers Alexander Mühleip and Alexey Amunts from Stockholm University solved the structure of a mitochondrial ATP synthase with native lipids.