In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a recently developed technology used in cancer research and in the pharmacological treatment of other diseases such as oral lesions. In ...

A plethora of studies have documented that gene expression profiling using DNA microarrays for various types of hematological malignancies provides novel information, which may have diagnostic and ...

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...

BUFFALO, N.Y. -- A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in ...

Here we present a method for the fabrication of microarrays in which presynthesized oligonucleotides are ejected onto a glass surface by a Bubble Jet printing device. The oligonucleotides are then ...

Genetic abnormalities have been associated with 6 to 13% of stillbirths, but the true prevalence may be higher. Unlike karyotype analysis, microarray analysis does not require live cells, and it ...

As more governments across the globe start requiring food producers to label products containing genetically modified organisms (GMOs) or even restricting the products’ sale, analytical chemists have ...

Microarrays are a two-dimensional arrangement of biological samples, with samples placed in spots numbering in the thousands and organized into columns and rows. They allow for efficient analysis of ...

Chromosomal microarray analysis has emerged as a primary diagnostic tool for the evaluation of developmental delay and structural malformations in children. We aimed to evaluate the accuracy, efficacy ...