The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

Different applications have different requirements, so researchers need to carefully weigh their options when deciding whether to switch to a new platform. [© WavebreakmediaMicro – Fotolia.com] With ...

Microarrays can be manufactured to different sizes with the number of probes on a microarray ranging from ten to five million. The fabrication of microarrays, particularly how the probes are ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...

Carbohydrate microarrays have become essential screening tools for revealing the functions of biomolecules that interact with sugars, providing essential information on the mechanisms of diseases. The ...

Microarrays are a two-dimensional arrangement of biological samples, with samples placed in spots numbering in the thousands and organized into columns and rows. They allow for efficient analysis of ...

Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays.

Jonathan Weissman at the University of California, San Francisco wants to know how cells fold proteins into the right shapes, and he knocks down genes to find out. For that he uses massive RNA ...

Editor's Note: To keep up with topical research trends, LabConsumer continues to address various aspects of microarray technology in 2000. "Array of Options" (May 29, 2000) described the features of ...