Nature

Subgroup Analysis in Clinical Trials

Subgroup analysis in clinical trials constitutes a vital methodological tool to uncover differential treatment effects within specified categories of patients. This approach enables researchers to ...
Open Heart

Thrombolysis in non-ST-elevation myocardial infarction: systematic review and meta-analysis of randomised controlled trials

Background Guidelines strongly recommend reperfusion therapy, including thrombolysis and percutaneous coronary intervention, ...
ascopubs.org

Low Programmed Death-Ligand 1–Expressing Subgroup Outcomes of First-Line Immune Checkpoint Inhibitors in Gastric or Esophageal Adenocarcinoma

Impact of Pembrolizumab Versus Chemotherapy as Second-Line Therapy for Advanced Esophageal Cancer on Health-Related Quality of Life in KEYNOTE-181 This study aims to reconstruct unreported ...
ascopubs.org

Efficacy of Maintenance Olaparib for Patients With Newly Diagnosed Advanced Ovarian Cancer With a BRCA Mutation: Subgroup Analysis Findings From the SOLO1 Trial

Volume Pledge is Not Associated with Better Short-Term Outcomes After Lung Cancer Resection The risk of disease progression or death was reduced with olaparib compared with placebo by 69% (HR, 0.31; ...
Morningstar

Neuronata-R® Stem Cell Therapy Shows Promise in ALS Phase 3 Subgroup Analysis, Moves Toward FDA Accelerated Approval

SEOUL, South Korea, May 29, 2025 /PRNewswire/ --Neuronata-R®, an autologous bone marrow-derived mesenchymal stem cell (MSC) therapy for amyotrophic lateral sclerosis (ALS), has demonstrated meaningful ...