Analysis of histological sections of disease tissues has traditionally relied on pathologist-based scoring. In an Advanced Online Publication in Nature Medicine Camp et al. describe techniques to ...

To study tissue samples from multiple patients, researchers use tissue microarrays (TMAs), a technology in which hundreds of tissue cores are arranged on a single glass slide for analysis by ...

MD Gustavson and DL Rimm are an employee and paid consultant, respectively, of Genoptix Medical Laboratory, which is the sole licensee of AQUA® technology, which is referenced and discussed in this ...

High-throughput tissue microarray allows many clinical specimens to be analyzed simultaneously on a single slide. One potential limitation of tissue microarray is the correct representation of each ...

Expression of CD24 and CD44 tumor cells in breast cancer patients who received neoadjuvant therapy. Background: Heat shock protein 27 (HSP27) is a stress-inducible protein preventing the accumulation ...

PURPOSE: E-cadherin (E-cad) and its associated intracellular molecules, catenins, are critical for intercellular epithelial adhesion and are often expressed in non–small-cell lung carcinomas (NSCLCs).

Emphasis on Potential Clinical Applications and Enhancing RNA Sample Quality Researchers are beginning to look at tissue microarrays (TMA) from different perspectives, including one with a strong ...

The method of choice used for preparing tissue samples can lead to biased results in the analysis of cancer patient survival. For microscopical analysis, full tissue samples provide a better picture ...

Accurate classification of tissue samples is an essential tool in disease diagnosis and treatment. The DNA microarray technology enables disease classification based only on gene expression analysis, ...

An SLAS Discovery original research report entitled "In Vitro Tissue Microarrays for Quick and Efficient Spheroid Characterization" describes a new technology that bridges the gap between clinical ...

With respect to assay development, quality assurance and, ultimately, clinical adoption, the primary subject of this review, these advantages are critical. Implicit with these advantages, TMAs enable ...